X-chromosome Reactivation Dynamics during Reprogramming (Pasque, Tchieu et al, Cell 2014)



Xist RNA spreading across the X chromosome (Engreitz et al, Science 2013)

Xist Spreading.pdf


Analysis of 3D genome organization in ESCs and during reprogramming and differentiation (Denholtz, Bonora et al, Cell Stem Cell, 2013)

4C paper


Reprogramming barriers (Sridharan et al, Nature Cell Biology, 2013)

Sridharan et al paper


Stage-specific effects of Wnt signaling (Ho, Papp et al, Cell Reports, 2013)

Ho et al


The inactive X does not reactivate during human cell reprogramming (Tchieu, Kuoy et al, Cell Stem Cell, 2010)



Our comparison of human iPSCs and ESCs (Chin et al Cell Stem Cell, 2009, 2010)

Chin et al 2010


Our first look at reprogramming factor binding in iPSCs and

pre-iPSCs (Sridharan, Tchieu, Mason et al, Cell 2009)